| Date | Time | Opponent | Score | |
| Fri, 8/27/2021 | 7:00 PM | at West Chester Henderson | 14 - 27 | Loss |
| Thu, 9/2/2021 | 7:00 PM | vs Annville-Cleona | 38 - 14 | Win |
| Fri, 9/10/2021 | 7:00 PM | at Upper Perkiomen | 41 - 0 | Win |
| Fri, 9/17/2021 | 7:00 PM | at Conrad Weiser | 38 - 52 | Loss |
| Fri, 9/24/2021 | 7:00 PM | vs Wyomissing | 7 - 48 | Loss |
| Sat, 10/2/2021 | 7:00 PM | vs Twin Valley | 26 - 9 | Win |
| Fri, 10/8/2021 | 7:00 PM | at Schuylkill Valley | 43 - 27 | Win |
| Fri, 10/15/2021 | 7:00 PM | at Hamburg | 28 - 26 | Win |
| Fri, 10/22/2021 | 7:00 PM | vs Upper Dauphin | 29 - 46 | Loss |
| Fri, 10/29/2021 | 7:00 PM | vs Kutztown | 49 - 30 | Win |
| Fri, 11/5/2021 | 7:00 PM | vs Boyertown | 47 - 35 | Win |