| Date | Time | Opponent | Score |
| Sat, 8/28/2021 | 7:00 PM | vs Wyomissing | L 14-41 |
| Fri, 9/3/2021 | 7:00 PM | at Twin Valley | L 19-10 |
| Fri, 9/10/2021 | 7:00 PM | at Garden Spot | W 17-45 |
| Fri, 9/17/2021 | 7:00 PM | vs Conestoga Valley | W 27-12 |
| Fri, 9/24/2021 | 7:00 PM | at Ephrata | W 14-33 |
| Fri, 10/1/2021 | 7:00 PM | vs Berks Catholic | L 7-40 |
| Fri, 10/8/2021 | 7:00 PM | at Muhlenberg | W 7-34 |
| Fri, 10/15/2021 | 7:00 PM | vs Reading High | W 35-0 |
| Fri, 11/5/2021 | 7:00 PM | at Waynesboro | L 42-20 |
|