| Date | Time | Opponent | Score |
| Sat, 8/28/2021 | 7:00 PM | vs Central Dauphin East | W 24-21 |
| Fri, 9/3/2021 | 7:00 PM | at Dallastown | L 41-38 |
| Sat, 9/11/2021 | 7:00 PM | at Harrisburg | L 20-17 |
| Fri, 9/17/2021 | 7:00 PM | at Spring-Ford | W 13-26 |
| Fri, 9/24/2021 | 7:00 PM | at Cocalico | W 21-48 |
| Fri, 10/1/2021 | 7:00 PM | vs Cedar Crest | W 42-7 |
| Fri, 10/8/2021 | 7:00 PM | vs Penn Manor | W 48-14 |
| Fri, 10/15/2021 | 7:00 PM | at Hempfield | L 17-14 |
| Fri, 10/22/2021 | 7:00 PM | at McCaskey | W 21-62 |
| Fri, 10/29/2021 | 7:00 PM | at Wilson | L 21-14 |
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