| Date | Time | Opponent | Score |
| Fri, 8/27/2021 | 7:00 PM | vs Conestoga Valley | W 16-12 |
| Fri, 9/3/2021 | 7:00 PM | at Lampeter-Strasburg | L 31-0 |
| Fri, 9/10/2021 | 7:00 PM | vs Northeastern | W 21-9 |
| Fri, 9/17/2021 | 7:00 PM | at Warwick | W 28-30 |
| Fri, 9/24/2021 | 7:00 PM | at Solanco | W 17-21 |
| Fri, 10/1/2021 | 7:00 PM | vs Wilson | L 6-40 |
| Fri, 10/8/2021 | 7:00 PM | at Manheim Township | L 48-14 |
| Fri, 10/15/2021 | 7:00 PM | at McCaskey | W 17-21 |
| Fri, 10/22/2021 | 7:00 PM | vs Cedar Crest | L 15-40 |
| Fri, 10/29/2021 | 7:00 PM | vs Hempfield | L 0-27 |
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