| Date | Time | Opponent | Score |
| Fri, 3/25/2022 | 4:15 PM | at Lancaster McCaskey | W 0-26 |
| Tue, 3/29/2022 | 4:15 PM | at Eastern Lebanon | W 9-12 |
| Wed, 3/30/2022 | 4:00 PM | vs Tulpehocken | W 9-1 |
| Fri, 4/1/2022 | 3:30 PM | vs Schuylkill Valley | W 15-5 |
| Sat, 4/2/2022 | 12:00 PM | vs Exeter | L 2-4 |
| Tue, 4/5/2022 | 4:00 PM | vs Berks Catholic | L 2-13 |
| Fri, 4/8/2022 | 4:00 PM | at Hamburg | L 8-4 |
| Mon, 4/11/2022 | 4:00 PM | vs Muhlenberg | W 16-0 |
| Wed, 4/13/2022 | 4:00 PM | vs Gov. Mifflin | L 1-2 |
| Wed, 4/20/2022 | 4:00 PM | at Wyomissing | W 6-13 |
| Thu, 4/21/2022 | 4:00 PM | vs Twin Valley | L 4-14 |
| Sat, 4/23/2022 | 11:00 AM | at Oley Valley | W 3-15 |
| Mon, 4/25/2022 | 4:00 PM | at Daniel Boone | W 5-8 |
| Tue, 4/26/2022 | 4:15 PM | at Cocalico | W 0-14 |
| Wed, 4/27/2022 | 4:00 PM | vs Reading High | W 16-1 |
| Fri, 4/29/2022 | 4:00 PM | at Twin Valley | L 10-6 |
| Mon, 5/2/2022 | 4:00 PM | vs Hamburg | L 0-13 |
| Wed, 5/4/2022 | 4:00 PM | at Muhlenberg | W 1-18 |
| Tue, 5/10/2022 | 4:00 PM | at Wilson | L 3-2 |
| Mon, 5/23/2022 | 4:30 PM | vs Kennard-Dale | W 8-4 |
| Thu, 5/26/2022 | 4:30 PM | at Hamburg | L 9-2 |
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