| Date | Time | Opponent | Score |
| Fri, 9/3/2021 | 4:00 PM | at Great Valley | W 36-19 |
| Fri, 9/3/2021 | 4:00 PM | at Downingtown East | W 29-26 |
| Tue, 9/7/2021 | 4:30 PM | at Fleetwood | W 50-15 |
| Tue, 9/7/2021 | 4:30 PM | at Gov. Mifflin | W 31-24 |
| Tue, 9/7/2021 | 4:30 PM | at Schuylkill Valley | W 43-20 |
| Tue, 9/14/2021 | 4:30 PM | vs Conrad Weiser | W 17-46 |
| Tue, 9/14/2021 | 4:30 PM | vs Exeter | W 25-31 |
| Tue, 9/14/2021 | 4:30 PM | vs Wyomissing | W 20-41 |
| Tue, 9/21/2021 | 4:30 PM | at Hamburg | W 50-15 |
| Tue, 9/21/2021 | 4:30 PM | at Tulpehocken | W 46-17 |
| Tue, 9/21/2021 | 4:30 PM | at Reading High | W 50-15 |
| Tue, 10/5/2021 | 4:30 PM | at Muhlenberg | W 50-15 |
| Tue, 10/5/2021 | 4:30 PM | vs Berks Catholic | W 16-45 |
| Tue, 10/5/2021 | 4:30 PM | vs Kutztown | W 18-42 |
| Tue, 10/12/2021 | 4:30 PM | vs Wilson | W 25-32 |
| Tue, 10/12/2021 | 4:30 PM | vs Daniel Boone | W 19-42 |
| Tue, 10/12/2021 | 4:30 PM | vs Oley Valley | W 18-45 |
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