| Date | Time | Opponent | Score |
| Tue, 9/7/2021 | 4:30 PM | vs Daniel Boone | L 50-15 |
| Tue, 9/7/2021 | 4:30 PM | at Kutztown | L 15-50 |
| Tue, 9/7/2021 | 4:30 PM | at Wyomissing | L 15-50 |
| Tue, 9/14/2021 | 4:30 PM | vs Berks Catholic | L 50-15 |
| Tue, 9/14/2021 | 4:30 PM | vs Gov. Mifflin | L 50-15 |
| Tue, 9/14/2021 | 4:30 PM | at Wilson | L 15-50 |
| Tue, 9/21/2021 | 4:30 PM | at Tulpehocken | L 15-50 |
| Tue, 9/21/2021 | 4:30 PM | vs Twin Valley | L 50-15 |
| Tue, 10/5/2021 | 4:30 PM | vs Oley Valley | L 50-15 |
| Tue, 10/5/2021 | 4:30 PM | vs Schuylkill Valley | L 50-15 |
| Tue, 10/5/2021 | 4:30 PM | vs Conrad Weiser | L 50-15 |
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