| Date | Time | Opponent | Score |
| Tue, 9/7/2021 | 4:30 PM | vs Berks Catholic | L 50-15 |
| Tue, 9/7/2021 | 4:30 PM | at Exeter | L 15-50 |
| Tue, 9/7/2021 | 4:30 PM | vs Oley Valley | L 50-15 |
| Tue, 9/14/2021 | 4:30 PM | at Schuylkill Valley | L 15-50 |
| Tue, 9/14/2021 | 7:00 PM | at Daniel Boone | L 15-50 |
| Tue, 9/21/2021 | 4:30 PM | vs Twin Valley | L 50-15 |
| Tue, 9/21/2021 | 4:30 PM | vs Tulpehocken | L 50-15 |
| Tue, 10/5/2021 | 4:30 PM | at Wyomissing | L 15-50 |
| Tue, 10/5/2021 | 4:30 PM | at Fleetwood | L 15-50 |
| Tue, 10/5/2021 | 4:30 PM | vs Wilson | L 50-15 |
| Tue, 10/12/2021 | 4:30 PM | vs Gov. Mifflin | L 50-15 |
| Tue, 10/12/2021 | 4:30 PM | at Kutztown | L 15-48 |
| Tue, 10/12/2021 | 7:00 PM | vs Conrad Weiser | L 44-17 |
|