| Date | Time | Opponent | Score |
| Tue, 9/7/2021 | 4:30 PM | vs Fleetwood | W 15-50 |
| Tue, 9/7/2021 | 4:30 PM | at Schuylkill Valley | W 43-20 |
| Tue, 9/7/2021 | 4:30 PM | vs Twin Valley | L 31-24 |
| Tue, 9/14/2021 | 4:30 PM | at Wilson | W 34-21 |
| Tue, 9/14/2021 | 4:30 PM | vs Berks Catholic | W 18-42 |
| Tue, 9/14/2021 | 4:30 PM | at Hamburg | W 50-15 |
| Tue, 9/21/2021 | 4:30 PM | at Muhlenberg | W 50-15 |
| Tue, 9/21/2021 | 4:30 PM | at Wyomissing | W 47-15 |
| Tue, 9/21/2021 | 4:30 PM | at Oley Valley | W 43-20 |
| Tue, 10/5/2021 | 4:30 PM | vs Tulpehocken | W 19-42 |
| Tue, 10/5/2021 | 4:30 PM | vs Exeter | W 19-36 |
| Tue, 10/5/2021 | 4:30 PM | vs Daniel Boone | W 15-48 |
| Tue, 10/12/2021 | 4:30 PM | vs Conrad Weiser | W 19-43 |
| Tue, 10/12/2021 | 4:30 PM | at Reading High | W 50-15 |
| Tue, 10/12/2021 | 4:30 PM | at Kutztown | W 42-20 |
|