| Date | Time | Opponent | Score |
| Tue, 12/21/2021 | 6:30 PM | at Tulpehocken | W 11-60 |
| Wed, 12/22/2021 | 6:30 PM | vs Kutztown | W 66-6 |
| Tue, 1/11/2022 | 7:00 PM | at Conrad Weiser | L 48-30 |
| Wed, 1/12/2022 | 6:30 PM | vs Wyomissing | W 44-30 |
| Wed, 1/19/2022 | 6:30 PM | vs Twin Valley | W 48-12 |
| Thu, 1/20/2022 | 6:30 PM | vs Schuylkill Valley | W 48-28 |
| Sat, 1/22/2022 | 12:00 PM | at Pine Grove | W 18-48 |
| Sat, 1/22/2022 | 2:00 PM | at Saucon Valley | L 72-0 |
| Sat, 1/22/2022 | 5:00 PM | at Northern Lebanon | L 57-15 |
| Mon, 1/24/2022 | 6:30 PM | vs Berks Catholic | L 23-39 |
| Wed, 1/26/2022 | 6:30 PM | at Oley Valley | W 34-41 |
| Fri, 1/28/2022 | 4:00 PM | at Gov. Mifflin | L 51-19 |
| Mon, 1/31/2022 | 6:00 PM | at West Perry | L 63-12 |
| Sat, 2/12/2022 | 9:00 AM | at Pequea Valley | W 15-51 |
| Sat, 2/12/2022 | 10:15 AM | at Annville-Cleona | W 18-54 |
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