| Date | Time | Opponent | Score |
| Sat, 12/11/2021 | 7:00 PM | vs Annville-Cleona | L 21-51 |
| Sat, 12/11/2021 | 7:00 PM | vs Biglerville | L 18-48 |
| Sat, 12/11/2021 | 7:00 PM | vs Hamburg | L 24-51 |
| Sat, 12/11/2021 | 7:00 PM | vs State College | L 9-66 |
| Wed, 12/15/2021 | 6:30 PM | at Gov. Mifflin | L 75-0 |
| Sat, 12/18/2021 | 6:00 PM | vs Schuylkill Valley | L 21-60 |
| Sat, 12/18/2021 | 7:00 PM | at Halifax | W 18-38 |
| Sat, 12/18/2021 | 7:00 PM | at Littlestown | W 6-57 |
| Thu, 1/6/2022 | 6:30 PM | vs Exeter | L 6-69 |
| Sat, 1/8/2022 | 9:00 AM | at Milton Hershey | L 57-18 |
| Sat, 1/8/2022 | 11:00 AM | at Kennard-Dale | W 27-30 |
| Sat, 1/8/2022 | 1:00 PM | at Haverford | L 58-18 |
| Sat, 1/8/2022 | 3:00 PM | at Twin Valley | L 34-30 |
| Sat, 1/8/2022 | 5:00 PM | at Pine Grove | L 36-35 |
| Wed, 1/12/2022 | 6:30 PM | vs Wilson | L 12-60 |
| Wed, 1/19/2022 | 6:30 PM | at Daniel Boone | L 58-6 |
| Thu, 1/20/2022 | 6:30 PM | vs Garden Spot | L 9-62 |
| Wed, 1/26/2022 | 6:30 PM | vs Muhlenberg | L 22-44 |
| Thu, 1/27/2022 | 7:00 PM | at Hamburg | L 56-18 |
| Wed, 2/2/2022 | 7:00 PM | at Norristown | L 48-23 |
| Thu, 2/3/2022 | 7:00 PM | at Elco | L 72-6 |
| Thu, 2/3/2022 | 7:00 PM | at Kutztown | W 24-36 |
| Thu, 2/3/2022 | 7:00 PM | at Avon Grove | L 51-24 |
| Wed, 2/9/2022 | 7:00 PM | at Wyomissing | L 51-24 |
| Thu, 2/10/2022 | 6:30 PM | vs Schuylkill Valley | L 6-63 |
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