| Date | Time | Opponent | Score |
| Tue, 9/7/2021 | 5:00 PM | vs Fleetwood | W 15-50 |
| Tue, 9/7/2021 | 5:00 PM | at Twin Valley | W 44-17 |
| Tue, 9/7/2021 | 5:00 PM | at Schuylkill Valley | W 50-15 |
| Tue, 9/14/2021 | 5:00 PM | vs Berks Catholic | W 15-46 |
| Tue, 9/14/2021 | 5:00 PM | at Wilson | W 29-28 |
| Tue, 9/14/2021 | 5:00 PM | at Hamburg | W 50-15 |
| Tue, 9/21/2021 | 5:00 PM | at Wyomissing | W 46-15 |
| Tue, 9/21/2021 | 5:00 PM | at Oley Valley | W 41-20 |
| Tue, 10/5/2021 | 5:00 PM | vs Tulpehocken | W 15-50 |
| Tue, 10/5/2021 | 5:00 PM | vs Daniel Boone | W 15-46 |
| Tue, 10/5/2021 | 5:00 PM | vs Exeter | W 20-35 |
| Tue, 10/12/2021 | 5:00 PM | vs Conrad Weiser | W 20-41 |
| Tue, 10/12/2021 | 5:00 PM | at Reading High | W 50-15 |
| Tue, 10/12/2021 | 5:00 PM | at Kutztown | W 49-15 |
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