| Date | Time | Opponent | Score |
| Fri, 8/26/2022 | 7:00 PM | at Daniel Boone | W 0-35 |
| Fri, 9/2/2022 | 7:00 PM | vs Boyertown | W 37-21 |
| Fri, 9/9/2022 | 7:00 PM | vs West York | W 35-0 |
| Fri, 9/16/2022 | 7:00 PM | at Gov. Mifflin | W 6-36 |
| Fri, 9/23/2022 | 7:00 PM | at Lebanon | W 22-69 |
| Fri, 9/30/2022 | 7:00 PM | vs Warwick | W 47-7 |
| Fri, 10/7/2022 | 7:00 PM | vs Muhlenberg | W 42-8 |
| Fri, 10/14/2022 | 7:00 PM | at Hempfield | W 22-44 |
| Fri, 10/21/2022 | 7:00 PM | vs Conestoga Valley | W 38-10 |
| Fri, 10/28/2022 | 7:00 PM | at Manheim Central | W 17-21 |
| Sat, 11/12/2022 | 7:00 PM | vs Dover | W 42-12 |
| Fri, 11/18/2022 | 7:00 PM | vs Northern York | W 21-7 |
| Fri, 11/25/2022 | 7:00 PM | vs Cocalico | L 14-34 |
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