| Date | Time | Opponent | Score |
| Fri, 9/2/2022 | 3:00 PM | vs Holy Ghost Prep | W 16-45 |
| Fri, 9/2/2022 | 3:00 PM | vs Downingtown East | W 19-41 |
| Fri, 9/2/2022 | 3:00 PM | vs Great Valley | W 19-42 |
| Fri, 9/2/2022 | 3:00 PM | vs Perkiomen Valley | W 17-44 |
| Tue, 9/6/2022 | 4:00 PM | vs Schuylkill Valley | W 15-48 |
| Tue, 9/6/2022 | 4:00 PM | at Hamburg | W 50-15 |
| Tue, 9/6/2022 | 4:30 PM | vs Gov. Mifflin | W 23-34 |
| Tue, 9/13/2022 | 4:30 PM | at Wilson | W 45-18 |
| Tue, 9/13/2022 | 4:30 PM | at Wyomissing | W 43-18 |
| Tue, 9/13/2022 | 4:30 PM | vs Fleetwood | W 17-46 |
| Tue, 9/20/2022 | 4:30 PM | vs Oley Valley | W 17-46 |
| Tue, 9/20/2022 | 4:30 PM | vs Reading High | W 15-50 |
| Tue, 9/20/2022 | 4:30 PM | vs Tulpehocken | W 23-37 |
| Tue, 10/4/2022 | 4:30 PM | vs Exeter | L 29-28 |
| Tue, 10/4/2022 | 4:30 PM | at Berks Catholic | W 50-15 |
| Tue, 10/4/2022 | 4:30 PM | vs Conrad Weiser | W 15-50 |
| Tue, 10/11/2022 | 4:30 PM | vs Daniel Boone | W 15-50 |
| Tue, 10/11/2022 | 4:30 PM | at Kutztown | W 41-18 |
| Tue, 10/11/2022 | 4:30 PM | vs Muhlenberg | W 15-50 |
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