| Date | Time | Opponent | Score |
| Tue, 9/6/2022 | 4:30 PM | at Wilson | L 15-49 |
| Tue, 9/6/2022 | 4:30 PM | vs Oley Valley | W 20-40 |
| Tue, 9/6/2022 | 4:30 PM | vs Kutztown | L 43-16 |
| Tue, 9/13/2022 | 4:30 PM | vs Hamburg | W 16-46 |
| Tue, 9/13/2022 | 4:30 PM | vs Reading High | W 15-50 |
| Tue, 9/13/2022 | 4:30 PM | at Daniel Boone | W 36-20 |
| Tue, 9/20/2022 | 4:30 PM | at Fleetwood | W 33-22 |
| Tue, 9/20/2022 | 4:30 PM | vs Schuylkill Valley | W 27-28 |
| Tue, 9/20/2022 | 4:30 PM | vs Muhlenberg | W 18-38 |
| Tue, 10/4/2022 | 4:30 PM | vs Twin Valley | L 50-15 |
| Tue, 10/4/2022 | 4:30 PM | vs Conrad Weiser | L 45-15 |
| Tue, 10/4/2022 | 4:30 PM | vs Exeter | L 50-15 |
| Tue, 10/11/2022 | 4:30 PM | at Tulpehocken | L 16-40 |
| Tue, 10/11/2022 | 4:30 PM | vs Gov. Mifflin | L 50-15 |
| Tue, 10/11/2022 | 4:30 PM | vs Wyomissing | L 48-15 |
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