| Date | Time | Opponent | Score |
| Tue, 9/6/2022 | 4:30 PM | at Exeter | L 18-45 |
| Tue, 9/6/2022 | 4:30 PM | vs Muhlenberg | W 15-50 |
| Tue, 9/6/2022 | 4:30 PM | vs Reading High | W 15-50 |
| Tue, 9/13/2022 | 4:30 PM | vs Twin Valley | L 43-18 |
| Tue, 9/13/2022 | 4:30 PM | vs Wilson | W 22-33 |
| Tue, 9/13/2022 | 4:30 PM | vs Fleetwood | W 19-44 |
| Tue, 9/20/2022 | 4:30 PM | vs Conrad Weiser | W 15-40 |
| Tue, 9/20/2022 | 4:30 PM | vs Hamburg | W 15-50 |
| Tue, 9/20/2022 | 4:30 PM | at Kutztown | W 39-16 |
| Thu, 10/6/2022 | 4:30 PM | vs Oley Valley | W 20-42 |
| Thu, 10/6/2022 | 4:30 PM | vs Daniel Boone | W 15-48 |
| Thu, 10/6/2022 | 4:30 PM | vs Schuylkill Valley | W 20-40 |
| Tue, 10/11/2022 | 4:30 PM | at Tulpehocken | W 35-21 |
| Tue, 10/11/2022 | 4:30 PM | at Berks Catholic | W 48-15 |
| Tue, 10/11/2022 | 4:30 PM | vs Gov. Mifflin | L 32-25 |
|