| Date | Time | Opponent | Score |
| Tue, 9/6/2022 | 4:00 PM | at Wilson | L 19-44 |
| Tue, 9/6/2022 | 4:30 PM | at Berks Catholic | L 20-40 |
| Tue, 9/6/2022 | 4:30 PM | vs Kutztown | L 39-20 |
| Tue, 9/13/2022 | 4:30 PM | vs Muhlenberg | W 25-33 |
| Tue, 9/13/2022 | 4:30 PM | vs Gov. Mifflin | L 44-19 |
| Tue, 9/13/2022 | 4:30 PM | vs Conrad Weiser | L 40-20 |
| Tue, 9/20/2022 | 4:30 PM | at Twin Valley | L 17-46 |
| Tue, 9/20/2022 | 4:30 PM | at Tulpehocken | L 18-45 |
| Tue, 9/20/2022 | 4:30 PM | at Reading High | W 50-15 |
| Thu, 10/6/2022 | 4:30 PM | at Schuylkill Valley | L 25-30 |
| Thu, 10/6/2022 | 4:30 PM | at Wyomissing | L 20-42 |
| Thu, 10/6/2022 | 4:30 PM | at Daniel Boone | W 34-25 |
| Tue, 10/11/2022 | 4:00 PM | at Hamburg | W 37-18 |
| Tue, 10/11/2022 | 4:30 PM | vs Exeter | L 46-17 |
| Tue, 10/11/2022 | 4:30 PM | vs Fleetwood | W 22-33 |
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