| Date | Time | Opponent | Score |
| Tue, 9/6/2022 | 4:30 PM | at Tulpehocken | L 21-40 |
| Tue, 9/6/2022 | 4:30 PM | at Conrad Weiser | L 20-41 |
| Tue, 9/6/2022 | 4:30 PM | vs Daniel Boone | L 29-26 |
| Tue, 9/13/2022 | 4:30 PM | at Wilson | L 19-44 |
| Tue, 9/13/2022 | 4:30 PM | at Twin Valley | L 17-46 |
| Tue, 9/13/2022 | 4:30 PM | at Wyomissing | L 19-44 |
| Tue, 9/20/2022 | 4:30 PM | vs Schuylkill Valley | L 36-24 |
| Tue, 9/20/2022 | 4:30 PM | vs Muhlenberg | W 22-36 |
| Tue, 9/20/2022 | 4:30 PM | vs Berks Catholic | L 33-22 |
| Tue, 10/4/2022 | 4:30 PM | at Kutztown | L 22-33 |
| Tue, 10/4/2022 | 4:30 PM | at Reading High | W 50-15 |
| Tue, 10/4/2022 | 4:30 PM | at Gov. Mifflin | L 19-44 |
| Tue, 10/11/2022 | 4:00 PM | at Hamburg | W 35-20 |
| Tue, 10/11/2022 | 4:30 PM | at Oley Valley | L 22-33 |
| Tue, 10/11/2022 | 4:30 PM | vs Exeter | L 50-15 |
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