| Date | Time | Opponent | Score |
| Thu, 9/1/2022 | 7:00 PM | vs Reading High | W 20-8 |
| Thu, 9/8/2022 | 7:00 PM | at Central York | W 9-20 |
| Sat, 9/10/2022 | 1:10 PM | at North Allegheny | L 24-7 |
| Sat, 9/10/2022 | 2:00 PM | at Cathedral Prep | W 5-9 |
| Sat, 9/10/2022 | 4:30 PM | at McDowell | W 2-16 |
| Tue, 9/13/2022 | 7:00 PM | at Exeter | W 8-19 |
| Thu, 9/15/2022 | 7:00 PM | vs Cumberland Valley | W 19-15 |
| Sat, 9/17/2022 | 3:30 PM | vs La Salle College | L 9-16 |
| Sat, 9/17/2022 | 5:10 PM | at Wissahickon | L 11-10 |
| Sat, 9/17/2022 | 7:40 PM | at Springfield (Delaware County) | W 9-18 |
| Tue, 9/20/2022 | 5:30 PM | vs Muhlenberg | W 22-18 |
| Thu, 9/22/2022 | 6:00 PM | at Mechanicsburg | W 8-14 |
| Fri, 9/23/2022 | 5:00 PM | vs North Allegheny | L 0-5 |
| Fri, 9/23/2022 | 7:00 PM | vs Wilson B | W 15-4 |
| Sat, 9/24/2022 | 12:00 PM | vs Brunswick B | L 8-13 |
| Sat, 9/24/2022 | 5:00 PM | vs Spalding | W 18-13 |
| Thu, 9/29/2022 | 3:45 PM | vs Wilson | L 11-18 |
| Tue, 10/4/2022 | 4:30 PM | at Muhlenberg | L 17-15 |
| Sat, 10/8/2022 | 8:50 AM | vs Souderton | W 17-13 |
| Sat, 10/8/2022 | 12:10 PM | vs Upper Dublin | W 14-9 |
| Sat, 10/8/2022 | 8:30 PM | vs Perkiomen Valley | W 18-10 |
| Tue, 10/11/2022 | 6:30 PM | vs Central York | W 19-10 |
| Thu, 10/13/2022 | 5:30 PM | at Cumberland Valley | L 13-12 |
| Tue, 10/18/2022 | 6:30 PM | vs Pennridge | W 14-4 |
| Thu, 10/20/2022 | 7:30 PM | at Wilson | L 21-11 |
| Fri, 10/28/2022 | 7:00 PM | vs North Allegheny | L 9-20 |
| Sat, 10/29/2022 | 10:00 AM | vs Cathedral Prep | W 13-10 |
| Sat, 10/29/2022 | 5:15 PM | vs La Salle College | W 13-9 |
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