| Date | Time | Opponent | Score |
| Tue, 9/6/2022 | 4:30 PM | at Wilson | L 22-39 |
| Tue, 9/6/2022 | 4:30 PM | vs Oley Valley | W 19-40 |
| Tue, 9/6/2022 | 4:30 PM | vs Kutztown | W 15-50 |
| Tue, 9/13/2022 | 4:30 PM | vs Hamburg | W 15-50 |
| Tue, 9/13/2022 | 4:30 PM | vs Reading High | W 15-50 |
| Tue, 9/13/2022 | 4:30 PM | at Daniel Boone | W 30-25 |
| Tue, 9/20/2022 | 4:30 PM | at Fleetwood | W 47-15 |
| Tue, 9/20/2022 | 4:30 PM | vs Schuylkill Valley | W 18-41 |
| Tue, 9/20/2022 | 4:30 PM | vs Muhlenberg | W 17-44 |
| Tue, 10/4/2022 | 4:30 PM | vs Twin Valley | L 42-17 |
| Tue, 10/4/2022 | 4:30 PM | vs Conrad Weiser | L 34-22 |
| Tue, 10/4/2022 | 4:30 PM | vs Exeter | L 45-16 |
| Tue, 10/11/2022 | 4:30 PM | at Tulpehocken | W 33-24 |
| Tue, 10/11/2022 | 4:30 PM | vs Gov. Mifflin | L 37-22 |
| Tue, 10/11/2022 | 4:30 PM | vs Wyomissing | L 30-25 |
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