| Date | Time | Opponent | Score |
| Tue, 9/6/2022 | 4:30 PM | at Tulpehocken | L 17-38 |
| Tue, 9/6/2022 | 4:30 PM | at Conrad Weiser | L 17-42 |
| Tue, 9/6/2022 | 4:30 PM | vs Daniel Boone | L 44-17 |
| Tue, 9/13/2022 | 4:30 PM | at Wilson | L 15-50 |
| Tue, 9/13/2022 | 4:30 PM | at Twin Valley | L 15-50 |
| Tue, 9/13/2022 | 4:30 PM | at Wyomissing | L 15-48 |
| Tue, 9/20/2022 | 4:30 PM | vs Schuylkill Valley | L 42-19 |
| Tue, 9/20/2022 | 4:30 PM | vs Muhlenberg | L 29-26 |
| Tue, 9/20/2022 | 4:30 PM | vs Berks Catholic | L 47-15 |
| Tue, 10/4/2022 | 4:30 PM | at Kutztown | W 50-15 |
| Tue, 10/4/2022 | 4:30 PM | at Reading High | W 30-27 |
| Tue, 10/4/2022 | 4:30 PM | at Gov. Mifflin | L 15-50 |
| Tue, 10/11/2022 | 4:30 PM | at Hamburg | W 50-15 |
| Tue, 10/11/2022 | 4:30 PM | at Oley Valley | W 29-26 |
| Tue, 10/11/2022 | 4:30 PM | vs Exeter | L 50-15 |
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