| Date | Time | Opponent | Score |
| Fri, 8/26/2022 | 10:00 AM | at Lower Dauphin | W 45-18 |
| Fri, 8/26/2022 | 10:00 AM | at Dallastown | L 25-32 |
| Tue, 9/6/2022 | 4:00 PM | at Hamburg | W 50-15 |
| Tue, 9/6/2022 | 4:30 PM | at Twin Valley | W 36-23 |
| Tue, 9/6/2022 | 4:30 PM | at Schuylkill Valley | W 50-15 |
| Tue, 9/13/2022 | 4:30 PM | at Oley Valley | W 43-20 |
| Tue, 9/13/2022 | 4:30 PM | at Muhlenberg | W 50-15 |
| Tue, 9/13/2022 | 4:30 PM | vs Conrad Weiser | W 20-43 |
| Tue, 9/20/2022 | 4:30 PM | vs Daniel Boone | W 15-47 |
| Tue, 9/20/2022 | 4:30 PM | at Exeter | L 27-29 |
| Tue, 9/20/2022 | 4:30 PM | at Wilson | W 40-20 |
| Tue, 10/4/2022 | 4:30 PM | vs Kutztown | W 15-50 |
| Tue, 10/4/2022 | 4:30 PM | vs Reading High | W 15-50 |
| Tue, 10/4/2022 | 4:30 PM | vs Fleetwood | W 15-50 |
| Tue, 10/11/2022 | 4:30 PM | at Tulpehocken | W 42-19 |
| Tue, 10/11/2022 | 4:30 PM | at Berks Catholic | W 37-22 |
| Tue, 10/11/2022 | 4:30 PM | at Wyomissing | W 37-22 |
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