| Date | Time | Opponent | Score |
| Tue, 9/6/2022 | 4:30 PM | at Exeter | L 15-50 |
| Tue, 9/6/2022 | 4:30 PM | at Reading High | W 50-15 |
| Tue, 9/6/2022 | 4:30 PM | at Wyomissing | L 15-50 |
| Tue, 9/13/2022 | 4:30 PM | at Oley Valley | L 24-31 |
| Tue, 9/13/2022 | 4:30 PM | vs Conrad Weiser | L 42-16 |
| Tue, 9/13/2022 | 4:30 PM | vs Gov. Mifflin | L 50-15 |
| Tue, 9/20/2022 | 4:30 PM | at Fleetwood | W 29-26 |
| Tue, 9/20/2022 | 4:30 PM | at Berks Catholic | L 17-44 |
| Tue, 9/20/2022 | 4:30 PM | at Schuylkill Valley | L 20-41 |
| Tue, 10/4/2022 | 4:00 PM | vs Tulpehocken | L 37-18 |
| Tue, 10/4/2022 | 4:00 PM | vs Wilson | L 50-15 |
| Tue, 10/4/2022 | 4:00 PM | vs Hamburg | W 15-50 |
| Tue, 10/11/2022 | 4:30 PM | at Kutztown | W 50-15 |
| Tue, 10/11/2022 | 4:30 PM | vs Daniel Boone | L 46-17 |
| Tue, 10/11/2022 | 4:30 PM | at Twin Valley | L 15-50 |
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