| Date | Time | Opponent | Score |
| Tue, 9/6/2022 | 4:30 PM | at Conrad Weiser | L 24-33 |
| Tue, 9/6/2022 | 4:30 PM | vs Daniel Boone | L 31-24 |
| Tue, 9/6/2022 | 4:30 PM | vs Fleetwood | W 17-38 |
| Tue, 9/13/2022 | 4:30 PM | vs Exeter | L 41-18 |
| Tue, 9/13/2022 | 4:30 PM | vs Kutztown | W 15-50 |
| Tue, 9/13/2022 | 4:30 PM | at Schuylkill Valley | W 33-22 |
| Tue, 9/20/2022 | 4:30 PM | at Twin Valley | L 16-43 |
| Tue, 9/20/2022 | 4:30 PM | vs Oley Valley | W 24-31 |
| Tue, 9/20/2022 | 4:30 PM | vs Reading High | W 15-40 |
| Tue, 10/4/2022 | 4:00 PM | at Muhlenberg | W 37-18 |
| Tue, 10/4/2022 | 4:30 PM | vs Hamburg | W 15-50 |
| Tue, 10/4/2022 | 4:30 PM | at Wilson | L 17-42 |
| Tue, 10/11/2022 | 4:30 PM | vs Wyomissing | L 36-21 |
| Tue, 10/11/2022 | 4:30 PM | vs Berks Catholic | L 33-24 |
| Tue, 10/11/2022 | 4:30 PM | vs Gov. Mifflin | L 42-19 |
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