| Date | Time | Opponent | Score |
| Fri, 9/2/2022 | 3:00 PM | vs Downingtown East | L 41-18 |
| Fri, 9/2/2022 | 3:00 PM | vs Great Valley | L 31-28 |
| Fri, 9/2/2022 | 3:00 PM | vs Perkiomen Valley | L 42-17 |
| Tue, 9/6/2022 | 4:00 PM | vs Schuylkill Valley | W 17-46 |
| Tue, 9/6/2022 | 4:00 PM | at Hamburg | W 50-15 |
| Tue, 9/6/2022 | 4:30 PM | vs Gov. Mifflin | L 36-23 |
| Tue, 9/13/2022 | 4:30 PM | at Wyomissing | W 35-21 |
| Tue, 9/13/2022 | 4:30 PM | at Wilson | W 31-24 |
| Tue, 9/13/2022 | 4:30 PM | vs Fleetwood | W 15-50 |
| Tue, 9/20/2022 | 4:30 PM | vs Oley Valley | W 19-44 |
| Tue, 9/20/2022 | 4:30 PM | vs Reading High | W 15-50 |
| Tue, 9/20/2022 | 4:30 PM | vs Tulpehocken | W 16-43 |
| Tue, 10/4/2022 | 4:30 PM | vs Exeter | L 33-22 |
| Tue, 10/4/2022 | 4:30 PM | at Berks Catholic | W 42-17 |
| Tue, 10/4/2022 | 4:30 PM | vs Conrad Weiser | W 23-34 |
| Tue, 10/11/2022 | 4:30 PM | vs Daniel Boone | W 18-43 |
| Tue, 10/11/2022 | 4:30 PM | at Kutztown | W 50-15 |
| Tue, 10/11/2022 | 4:30 PM | vs Muhlenberg | W 15-50 |
|