| Date | Time | Opponent | Score |
| Fri, 9/3/2010 | 7:00 PM | vs William Allen | W 49-6 |
| Fri, 9/10/2010 | 7:00 PM | at Twin Valley | W 6-42 |
| Fri, 9/17/2010 | 7:00 PM | vs Pottsgrove | W 34-28 |
| Sat, 9/25/2010 | 1:00 PM | at Pope John Paul II | W 13-35 |
| Sat, 10/2/2010 | 1:00 PM | at Phoenixville | W 19-44 |
| Fri, 10/8/2010 | 7:00 PM | vs Perkiomen Valley | W 26-14 |
| Fri, 10/15/2010 | 7:00 PM | at Pottstown | W 7-35 |
| Fri, 10/22/2010 | 7:00 PM | vs Spring-Ford | W 20-0 |
| Fri, 10/29/2010 | 7:00 PM | at Owen J. Roberts | L 55-14 |
| Fri, 11/5/2010 | 7:00 PM | vs Methacton | W 27-21 |
| Fri, 11/12/2010 | 7:00 PM | at Bayard Rustin | L 21-13 |
| Thu, 11/25/2010 | 10:00 AM | at Upper Perkiomen | W 27-55 |
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