| Date | Time | Opponent | Score |
| Sat, 9/4/2010 | 11:00 AM | at Lansdale Catholic | L 28-26 |
| Fri, 9/10/2010 | 7:00 PM | vs Souderton | L 0-39 |
| Fri, 9/17/2010 | 7:00 PM | vs Upper Perkiomen | W 26-14 |
| Fri, 9/24/2010 | 7:00 PM | at Pottsgrove | L 21-10 |
| Sat, 10/2/2010 | 1:00 PM | vs Pope John Paul II | W 22-6 |
| Fri, 10/8/2010 | 7:00 PM | at Boyertown | L 26-14 |
| Fri, 10/15/2010 | 7:00 PM | at Phoenixville | W 8-21 |
| Fri, 10/22/2010 | 7:00 PM | vs Pottstown | W 20-17 |
| Fri, 10/29/2010 | 7:00 PM | at Spring-Ford | L 28-0 |
| Fri, 11/5/2010 | 7:00 PM | vs Owen J. Roberts | L 7-32 |
| Sat, 11/13/2010 | 1:00 PM | at Methacton | W 0-21 |
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