| Date | Time | Opponent | Score |
| Fri, 9/3/2010 | 7:00 PM | vs Muhlenberg | W 49-35 |
| Sat, 9/11/2010 | 7:00 PM | vs Upper Dublin | L 14-27 |
| Fri, 9/17/2010 | 7:00 PM | at Perkiomen Valley | L 26-14 |
| Fri, 9/24/2010 | 7:00 PM | vs Pottstown | W 35-6 |
| Sat, 10/2/2010 | 1:00 PM | at Spring-Ford | L 42-34 |
| Fri, 10/8/2010 | 7:00 PM | vs Owen J. Roberts | L 20-55 |
| Thu, 10/14/2010 | 1:00 PM | at Methacton | W 35-42 |
| Fri, 10/22/2010 | 7:00 PM | vs Phoenixville | W 28-21 |
| Fri, 10/29/2010 | 7:00 PM | vs Pottsgrove | L 19-69 |
| Sat, 11/6/2010 | 1:00 PM | at Pope John Paul II | W 35-49 |
| Fri, 11/12/2010 | 7:00 PM | at Strath Haven | L 48-7 |
| Thu, 11/25/2010 | 10:00 AM | vs Boyertown | L 27-55 |
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