| Date | Time | Opponent | Score |
| Wed, 9/8/2010 | 4:00 PM | at Spring-Ford | W 36-22 |
| Wed, 9/15/2010 | 4:00 PM | at Methacton | W 30-25 |
| Wed, 9/15/2010 | 7:00 PM | vs Pope John Paul II | W 19-42 |
| Wed, 9/22/2010 | 4:00 PM | vs Perkiomen Valley | W 26-30 |
| Wed, 9/29/2010 | 4:00 PM | vs Upper Perkiomen | W 15-47 |
| Wed, 9/29/2010 | 7:00 PM | vs Pottstown | W 15-49 |
| Wed, 10/6/2010 | 4:00 PM | at Owen J. Roberts | W 36-23 |
| Wed, 10/6/2010 | 4:00 PM | at Phoenixville | W 49-15 |
| Wed, 10/13/2010 | 4:00 PM | at Pottsgrove | W 29-27 |
|