| Date | Time | Opponent | Score |
| Fri, 9/3/2010 | 7:00 PM | at Plymouth-Whitemarsh | L 13-6 |
| Fri, 9/10/2010 | 7:00 PM | at Upper Merion | W 7-14 |
| Fri, 9/17/2010 | 7:00 PM | at Pottstown | W 10-17 |
| Sat, 9/25/2010 | 1:00 PM | vs Spring-Ford | W 25-20 |
| Fri, 10/1/2010 | 7:00 PM | at Owen J. Roberts | L 42-7 |
| Sat, 10/9/2010 | 1:00 PM | vs Phoenixville | L 6-48 |
| Thu, 10/14/2010 | 1:00 PM | vs Upper Perkiomen | L 35-42 |
| Fri, 10/22/2010 | 7:00 PM | at Pottsgrove | L 49-0 |
| Sat, 10/30/2010 | 1:00 PM | vs Pope John Paul II | W 42-21 |
| Fri, 11/5/2010 | 7:00 PM | at Boyertown | L 27-21 |
| Sat, 11/13/2010 | 1:00 PM | vs Perkiomen Valley | L 0-21 |
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