| Date | Time | Opponent | Score |
| Wed, 9/8/2010 | 4:00 PM | at Spring-Ford | W 42-19 |
| Wed, 9/15/2010 | 4:00 PM | at Methacton | W 33-24 |
| Wed, 9/15/2010 | 7:00 PM | vs Pope John Paul II | W 17-46 |
| Wed, 9/22/2010 | 4:00 PM | vs Perkiomen Valley | W 15-47 |
| Wed, 9/29/2010 | 4:00 PM | vs Upper Perkiomen | W 15-44 |
| Wed, 9/29/2010 | 7:00 PM | vs Pottstown | W 15-50 |
| Wed, 10/6/2010 | 4:00 PM | at Owen J. Roberts | W 47-15 |
| Wed, 10/6/2010 | 4:00 PM | at Phoenixville | W 50-15 |
| Wed, 10/13/2010 | 4:00 PM | at Pottsgrove | W 36-22 |
|