| Date | Time | Opponent | Score |
| Sat, 8/28/2021 | 1:00 PM | at York Vo-Tech | W 20-47 |
| Fri, 9/3/2021 | 7:00 PM | vs Northern Lebanon | W 47-6 |
| Fri, 9/10/2021 | 7:00 PM | at Mahanoy | W 0-21 |
| Sat, 9/18/2021 | 1:30 PM | at Wyomissing | L 47-7 |
| Fri, 9/24/2021 | 7:00 PM | vs Tri-Valley | W 36-18 |
| Fri, 10/1/2021 | 7:00 PM | at Kutztown | W 34-47 |
| Fri, 10/8/2021 | 7:00 PM | vs Conrad Weiser | L 27-31 |
| Fri, 10/15/2021 | 7:00 PM | vs Fleetwood | L 26-28 |
| Fri, 10/29/2021 | 7:00 PM | at Schuylkill Valley | W 13-21 |
| Fri, 11/5/2021 | 7:00 PM | vs Bermudian Springs | W 31-27 |
| Fri, 11/12/2021 | 7:00 PM | at Boiling Springs | L 35-7 |
|