| Date | Time | Opponent | Score |
| Fri, 8/27/2021 | 7:00 PM | at Springfield (Montgomery County | L 35-7 |
| Fri, 9/3/2021 | 7:00 PM | vs Elco | L 6-21 |
| Fri, 9/10/2021 | 7:00 PM | at Pottsgrove | L 35-0 |
| Fri, 9/17/2021 | 7:00 PM | vs Upper Perkiomen | W 42-14 |
| Fri, 9/24/2021 | 7:00 PM | vs Kutztown | W 28-8 |
| Fri, 10/1/2021 | 7:00 PM | at Conrad Weiser | L 45-21 |
| Fri, 10/8/2021 | 7:00 PM | vs Fleetwood | L 27-43 |
| Fri, 10/15/2021 | 7:00 PM | at Twin Valley | L 42-14 |
| Sat, 10/23/2021 | 1:30 PM | at Wyomissing | L 49-0 |
| Fri, 10/29/2021 | 7:00 PM | vs Hamburg | L 13-21 |
| Fri, 11/5/2021 | 7:00 PM | at Nanticoke | L 21-14 |