| Date | Time | Opponent | Score |
| Fri, 12/10/2021 | 7:00 PM | at Downingtown East | L 46-23 |
| Sat, 12/11/2021 | 7:00 PM | at Allentown Central Catholic | L 54-32 |
| Tue, 12/14/2021 | 7:00 PM | vs Executive Education Academy Charter | L 34-58 |
| Sat, 12/18/2021 | 7:00 PM | at Kennett | L 45-27 |
| Tue, 12/21/2021 | 7:00 PM | vs Owen J. Roberts | L 30-59 |
| Thu, 12/23/2021 | 7:00 PM | vs Spring-Ford | L 21-52 |
| Tue, 12/28/2021 | 6:00 PM | vs Lansdale Catholic | L 30-60 |
| Wed, 12/29/2021 | 4:30 PM | vs Pennridge | L 47-66 |
| Thu, 1/6/2022 | 6:00 PM | at Methacton | L 77-32 |
| Sat, 1/8/2022 | 1:00 PM | at Wilson | L 53-34 |
| Tue, 1/11/2022 | 7:00 PM | at Perkiomen Valley | L 54-20 |
| Thu, 1/13/2022 | 7:00 PM | vs Upper Merion | W 61-24 |
| Fri, 1/14/2022 | 7:00 PM | vs Norristown | W 57-22 |
| Mon, 1/17/2022 | 6:00 PM | vs Pope John Paul II | L 34-50 |
| Tue, 1/18/2022 | 7:00 PM | at Owen J. Roberts | L 54-28 |
| Thu, 1/20/2022 | 6:00 PM | vs Phoenixville | W 37-28 |
| Sat, 1/22/2022 | 11:30 AM | vs Wyomissing | L 33-41 |
| Tue, 1/25/2022 | 7:00 PM | at Spring-Ford | L 58-26 |
| Thu, 1/27/2022 | 7:00 PM | vs Methacton | L 38-54 |
| Tue, 2/1/2022 | 7:00 PM | vs Perkiomen Valley | L 27-67 |
| Wed, 2/2/2022 | 7:00 PM | at Coatesville | L 53-39 |
| Thu, 2/3/2022 | 6:00 PM | at Norristown | W 47-57 |