| Date | Time | Opponent | Score |
| Fri, 12/10/2021 | 7:00 PM | at Collegium Charter School (Exton) | W 41-66 |
| Sat, 12/11/2021 | 7:00 PM | at Conestoga | L 59-41 |
| Tue, 12/14/2021 | 6:00 PM | at Lancaster McCaskey | W 56-57 |
| Thu, 12/16/2021 | 6:00 PM | at Exeter | W 47-51 |
| Sat, 12/18/2021 | 1:00 PM | vs Lebanon | W 63-57 |
| Mon, 12/20/2021 | 6:00 PM | vs Wilson | L 38-53 |
| Wed, 12/22/2021 | 6:00 PM | vs Cedar Crest | L 39-54 |
| Mon, 1/10/2022 | 6:00 PM | at Manheim Township | L 56-21 |
| Tue, 1/11/2022 | 6:00 PM | vs Gov. Mifflin | L 50-65 |
| Thu, 1/13/2022 | 6:00 PM | vs Conrad Weiser | W 48-38 |
| Tue, 1/18/2022 | 6:00 PM | at Twin Valley | L 45-35 |
| Fri, 1/21/2022 | 6:00 PM | at Daniel Boone | W 11-50 |
| Sat, 1/22/2022 | 12:00 PM | vs Allentown Allen | W 63-29 |
| Mon, 1/24/2022 | 6:00 PM | vs Exeter | W 62-28 |
| Tue, 1/25/2022 | 6:00 PM | at Berks Catholic | L 55-45 |
| Thu, 1/27/2022 | 6:00 PM | at Wilson | L 53-35 |
| Tue, 2/1/2022 | 6:00 PM | vs Berks Catholic | L 44-70 |
| Wed, 2/2/2022 | 6:00 PM | vs Susquehanna Township | W 47-39 |
| Sat, 2/5/2022 | 2:00 PM | vs Souderton | L 42-58 |
| Mon, 2/7/2022 | 6:00 PM | vs Muhlenberg | W 56-34 |
| Tue, 2/8/2022 | 6:00 PM | vs Harrisburg | W 54-43 |
| Wed, 2/9/2022 | 6:00 PM | at Gov. Mifflin | W 52-64 |
| Sat, 2/12/2022 | 2:00 PM | at Schuylkill Valley | W 33-43 |
| Tue, 2/15/2022 | 6:00 PM | at Wilson | L 37-34 |
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