| Date | Time | Opponent | Score |
| Fri, 12/10/2021 | 5:45 PM | at Kennett | L 48-5 |
| Sat, 12/11/2021 | 7:00 PM | at Downingtown West | L 57-9 |
| Tue, 12/14/2021 | 6:00 PM | vs Upper Perkiomen | L 8-55 |
| Thu, 12/16/2021 | 6:00 PM | at Muhlenberg | L 50-9 |
| Sat, 12/18/2021 | 12:00 PM | vs Schuylkill Valley | L 4-35 |
| Mon, 12/20/2021 | 6:00 PM | vs Conrad Weiser | L 8-48 |
| Wed, 12/22/2021 | 6:00 PM | at Oley Valley | L 60-20 |
| Mon, 12/27/2021 | 2:00 PM | at Wyomissing | L 51-13 |
| Tue, 12/28/2021 | 1:00 PM | at Phoenixville | L 41-26 |
| Tue, 1/4/2022 | 6:00 PM | vs Gov. Mifflin | L 10-62 |
| Sat, 1/8/2022 | 12:00 PM | vs Fleetwood | L 24-61 |
| Mon, 1/10/2022 | 6:00 PM | vs Twin Valley | L 10-47 |
| Thu, 1/13/2022 | 6:00 PM | vs Exeter | L 10-63 |
| Tue, 1/18/2022 | 6:00 PM | at Berks Catholic | L 46-7 |
| Fri, 1/21/2022 | 6:00 PM | vs Reading High | L 11-50 |
| Mon, 1/24/2022 | 6:00 PM | at Twin Valley | L 51-20 |
| Thu, 1/27/2022 | 6:00 PM | vs Muhlenberg | L 9-39 |
| Tue, 2/1/2022 | 6:00 PM | at Conrad Weiser | L 46-8 |
| Wed, 2/9/2022 | 6:00 PM | at Wilson | L 57-11 |
| Thu, 2/10/2022 | 6:00 PM | at Pottsgrove | L 40-19 |
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