| Date | Time | Opponent | Score |
| Fri, 12/10/2021 | 7:00 PM | at York Suburban | L 40-33 |
| Sat, 12/11/2021 | 12:00 PM | at Muhlenberg | W 37-52 |
| Tue, 12/14/2021 | 6:00 PM | at Bishop McDevitt | L 44-25 |
| Thu, 12/16/2021 | 6:00 PM | vs Twin Valley | L 29-32 |
| Sat, 12/18/2021 | 12:00 PM | vs Conrad Weiser | W 38-34 |
| Mon, 12/20/2021 | 6:00 PM | at Tulpehocken | W 40-56 |
| Mon, 12/27/2021 | 2:00 PM | vs Daniel Boone | W 51-13 |
| Tue, 1/4/2022 | 7:00 PM | at Fleetwood | L 49-33 |
| Mon, 1/10/2022 | 6:00 PM | at Hamburg | W 37-46 |
| Wed, 1/12/2022 | 6:00 PM | vs York Catholic | W 49-47 |
| Thu, 1/13/2022 | 6:00 PM | at Brandywine Heights | L 37-29 |
| Sat, 1/15/2022 | 12:00 PM | vs Schuylkill Valley | L 32-34 |
| Wed, 1/19/2022 | 6:00 PM | vs Kutztown | W 52-21 |
| Fri, 1/21/2022 | 6:00 PM | at Oley Valley | W 49-55 |
| Sat, 1/22/2022 | 11:30 AM | at Boyertown | W 33-41 |
| Tue, 1/25/2022 | 6:00 PM | vs Elco | W 41-28 |
| Thu, 1/27/2022 | 6:00 PM | vs Antietam | W 57-22 |
| Tue, 2/1/2022 | 6:00 PM | vs Fleetwood | W 47-17 |
| Thu, 2/3/2022 | 6:00 PM | at Linden Hall | L 52-20 |
| Fri, 2/4/2022 | 6:00 PM | at Schuylkill Valley | L 29-26 |
| Mon, 2/7/2022 | 6:00 PM | vs Hamburg | W 51-23 |
| Sat, 2/12/2022 | 2:00 PM | at Berks Catholic | L 52-34 |
| Tue, 2/22/2022 | 7:00 PM | at Bermudian Springs | L 77-48 |
|