| Date | Time | Opponent | Score |
| Fri, 12/10/2021 | 5:30 PM | vs Annville-Cleona | W 33-25 |
| Sat, 12/11/2021 | 4:30 PM | vs Brandywine Heights | L 25-45 |
| Tue, 12/14/2021 | 5:30 PM | at Tulpehocken | W 34-56 |
| Thu, 12/16/2021 | 6:00 PM | at Fleetwood | L 29-24 |
| Mon, 12/20/2021 | 6:00 PM | vs Schuylkill Valley | L 21-43 |
| Wed, 12/22/2021 | 5:30 PM | vs Twin Valley | L 26-45 |
| Mon, 12/27/2021 | 5:30 PM | vs Northwestern Lehigh | W 43-39 |
| Wed, 12/29/2021 | 5:30 PM | vs Blue Mountain | L 29-43 |
| Tue, 1/4/2022 | 6:00 PM | at Brandywine Heights | L 57-54 |
| Wed, 1/5/2022 | 6:00 PM | at Elco | L 38-22 |
| Mon, 1/10/2022 | 6:00 PM | vs Wyomissing | L 37-46 |
| Thu, 1/13/2022 | 6:00 PM | at Kutztown | W 8-44 |
| Sat, 1/15/2022 | 6:00 PM | vs Panther Valley | W 53-32 |
| Fri, 1/21/2022 | 6:00 PM | vs Antietam | W 45-9 |
| Sat, 1/22/2022 | 3:00 PM | at Pine Grove | L 51-15 |
| Mon, 1/24/2022 | 6:00 PM | vs Fleetwood | L 30-53 |
| Tue, 1/25/2022 | 7:00 PM | vs Oley Valley | L 53-56 |
| Thu, 1/27/2022 | 6:00 PM | at Schuylkill Valley | L 36-35 |
| Sat, 1/29/2022 | 7:00 PM | vs Northern Lebanon | W 43-37 |
| Tue, 2/1/2022 | 7:15 PM | vs Tulpehocken | W 37-24 |
| Fri, 2/4/2022 | 7:15 PM | vs Schuylkill Haven | W 49-27 |
| Mon, 2/7/2022 | 6:00 PM | at Wyomissing | L 51-23 |
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