| Date | Time | Opponent | Score |
| Fri, 12/10/2021 | 7:00 PM | vs Upper Perkiomen | L 26-54 |
| Sat, 12/11/2021 | 3:00 PM | vs Pequea Valley | L 26-50 |
| Tue, 12/14/2021 | 5:30 PM | vs Hamburg | L 34-56 |
| Thu, 12/16/2021 | 6:00 PM | at Oley Valley | L 59-28 |
| Mon, 12/20/2021 | 6:00 PM | vs Wyomissing | L 40-56 |
| Tue, 12/28/2021 | 5:30 PM | at Annville-Cleona | L 44-29 |
| Wed, 12/29/2021 | 3:30 PM | at Octorara | W 20-55 |
| Tue, 1/4/2022 | 6:00 PM | vs Kutztown | W 48-38 |
| Mon, 1/10/2022 | 6:00 PM | at Brandywine Heights | L 53-26 |
| Wed, 1/12/2022 | 6:30 PM | at Antietam | W 18-45 |
| Thu, 1/13/2022 | 6:00 PM | vs Schuylkill Valley | L 26-49 |
| Fri, 1/21/2022 | 6:00 PM | at Fleetwood | L 54-21 |
| Sat, 1/22/2022 | 2:30 PM | vs Conrad Weiser | L 32-45 |
| Mon, 1/24/2022 | 6:00 PM | vs Brandywine Heights | L 23-42 |
| Sat, 1/29/2022 | 4:00 PM | vs Schuylkill Haven | W 47-25 |
| Tue, 2/1/2022 | 7:15 PM | at Hamburg | L 37-24 |
| Wed, 2/2/2022 | 6:00 PM | vs Oley Valley | W 37-33 |
| Thu, 2/3/2022 | 6:00 PM | at Kutztown | L 38-26 |
| Sat, 2/5/2022 | 3:30 PM | at Upper Dauphin | L 43-36 |
| Tue, 2/8/2022 | 6:00 PM | vs Antietam | W 41-19 |
| Fri, 2/11/2022 | 6:00 PM | vs Veritas Academy | W 57-32 |
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