| Date | Time | Opponent | Score |
| Fri, 12/10/2021 | 6:00 PM | vs Ephrata | W 74-53 |
| Sat, 12/11/2021 | 7:00 PM | at Red Lion | W 42-76 |
| Wed, 12/15/2021 | 6:00 PM | vs Easton | W 59-51 |
| Fri, 12/17/2021 | 6:00 PM | at Daniel Boone | W 26-80 |
| Tue, 12/28/2021 | 5:00 PM | at Hazelton | W 59-68 |
| Wed, 12/29/2021 | 6:30 PM | at Allentown Allen | L 65-61 |
| Tue, 1/4/2022 | 6:00 PM | at Twin Valley | W 42-54 |
| Thu, 1/6/2022 | 6:00 PM | at Wilson | L 57-56 |
| Sat, 1/8/2022 | 1:00 PM | vs Solanco | W 78-44 |
| Mon, 1/10/2022 | 5:30 PM | at Dieruff | W 63-73 |
| Tue, 1/11/2022 | 6:00 PM | vs Conrad Weiser | W 64-57 |
| Fri, 1/14/2022 | 6:00 PM | at Gov. Mifflin | W 47-55 |
| Sat, 1/15/2022 | 3:00 PM | vs Nativity | L 76-82 |
| Mon, 1/17/2022 | 6:00 PM | vs Exeter | W 76-53 |
| Thu, 1/20/2022 | 6:00 PM | at Berks Catholic | L 80-64 |
| Fri, 1/21/2022 | 6:15 PM | vs Executive Education Academy Charter | L 62-67 |
| Sat, 1/22/2022 | 6:00 PM | vs Susquehanna Township | W 83-65 |
| Tue, 1/25/2022 | 6:00 PM | at Conrad Weiser | W 36-76 |
| Fri, 1/28/2022 | 6:00 PM | vs Daniel Boone | W 82-17 |
| Thu, 2/3/2022 | 6:00 PM | vs Twin Valley | W 85-40 |
| Sat, 2/5/2022 | 11:30 AM | vs Bethlehem Liberty | W 67-43 |
| Tue, 2/8/2022 | 6:00 PM | vs Reading High | W 63-61 |
| Mon, 2/14/2022 | 7:00 PM | vs Fleetwood | W 70-48 |
| Wed, 2/16/2022 | 8:00 PM | at Reading High | L 70-54 |
| Tue, 2/22/2022 | 7:00 PM | at Cedar Cliff | L 55-54 |
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