| Date | Time | Opponent | Score |
| Fri, 12/10/2010 | 6:30 PM | at Penn Manor | W 58-63 |
| Sat, 12/11/2010 | 8:00 PM | at Lampeter-Strasburg | W 60-69 |
| Fri, 12/17/2010 | 7:00 PM | vs Neumann Goretti | L 46-58 |
| Tue, 12/21/2010 | 6:15 PM | at Kutztown | W 40-82 |
| Thu, 12/23/2010 | 6:00 PM | at Parkland | W 34-45 |
| Mon, 12/27/2010 | 7:30 PM | vs Pottstown | W 66-53 |
| Tue, 12/28/2010 | 7:30 PM | vs Danville | W 52-44 |
| Tue, 1/4/2011 | 7:45 PM | at Antietam | W 49-63 |
| Thu, 1/6/2011 | 6:15 PM | vs Wyomissing | W 52-33 |
| Tue, 1/11/2011 | 4:00 PM | at Oley Valley | W 37-67 |
| Thu, 1/13/2011 | 6:15 PM | vs Holy Name | W 44-27 |
| Sun, 1/16/2011 | 1:00 PM | at Holy Redeemer | W 46-58 |
| Wed, 1/19/2011 | 6:15 PM | at Hamburg | W 28-71 |
| Thu, 1/20/2011 | 6:15 PM | at Schuylkill Valley | W 49-62 |
| Sat, 1/22/2011 | 3:00 PM | at Perkiomen Valley | W 52-62 |
| Sat, 1/29/2011 | 7:00 PM | at Philadelphia Roman Catholic | L 58-47 |
| Mon, 1/31/2011 | 6:00 PM | at Brandywine Heights | W 28-64 |
| Thu, 2/3/2011 | 4:00 PM | vs Kutztown | W 60-25 |
| Fri, 2/4/2011 | 7:30 PM | vs Antietam | W 65-36 |
| Mon, 2/7/2011 | 6:15 PM | at Holy Name | W 35-60 |
| Tue, 2/8/2011 | 6:15 PM | at Wyomissing | W 36-62 |
| Thu, 2/10/2011 | 6:45 PM | vs Tulpehocken | W 70-33 |
| Mon, 2/14/2011 | 8:00 PM | vs Wilson | W 42-34 |
| Wed, 2/16/2011 | 6:30 PM | at Muhlenberg | W 35-57 |
| Fri, 2/18/2011 | 8:00 PM | at Reading High | L 58-50 |
| Fri, 2/25/2011 | 6:30 PM | vs New Hope Academy | W 48-43 |
| Mon, 2/28/2011 | 6:00 PM | vs Lancaster Country Day | W 37-22 |
| Fri, 3/4/2011 | 5:00 PM | at Greenwood | W 18-24 |
| Fri, 3/11/2011 | 8:00 PM | vs Sayre | W 58-41 |
| Tue, 3/15/2011 | 8:00 PM | vs Old Forge | W 32-21 |
| Fri, 3/18/2011 | 6:00 PM | at Constitution | L 55-53 |
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