| Date | Time | Opponent | Score |
| Fri, 12/10/2010 | 6:00 PM | vs Mount St. Joseph | L 36-47 |
| Sat, 12/11/2010 | 6:00 PM | at Cumberland Valley | W 37-56 |
| Tue, 12/14/2010 | 6:30 PM | at Manheim Township | L 53-38 |
| Sat, 12/18/2010 | 1:00 PM | vs Pottsville | W 66-36 |
| Tue, 12/21/2010 | 6:15 PM | vs Twin Valley | W 68-30 |
| Thu, 12/23/2010 | 6:15 PM | at Oley Valley | L 68-54 |
| Mon, 12/27/2010 | 6:30 PM | vs Lancaster McCaskey | W 65-46 |
| Tue, 12/28/2010 | 8:00 PM | vs Lampeter-Strasburg | W 54-38 |
| Tue, 1/4/2011 | 6:15 PM | at Reading High | L 55-47 |
| Thu, 1/6/2011 | 6:15 PM | vs Exeter | W 71-30 |
| Sat, 1/8/2011 | 5:30 PM | at Hempfield | W 49-54 |
| Tue, 1/11/2011 | 5:00 PM | at Wilson | W 24-44 |
| Thu, 1/13/2011 | 6:00 PM | at Boyertown | L 47-36 |
| Sat, 1/15/2011 | 6:00 PM | vs William Allen | W 54-49 |
| Wed, 1/19/2011 | 6:15 PM | at Daniel Boone | W 56-59 |
| Thu, 1/20/2011 | 6:15 PM | vs Fleetwood | W 63-18 |
| Sat, 1/22/2011 | 1:00 PM | vs Holy Name | W 58-29 |
| Tue, 1/25/2011 | 6:15 PM | at Muhlenberg | W 33-40 |
| Fri, 1/28/2011 | 6:15 PM | at Conrad Weiser | W 30-54 |
| Wed, 2/2/2011 | 6:15 PM | vs Reading High | W 73-59 |
| Thu, 2/3/2011 | 6:15 PM | at Exeter | W 11-60 |
| Mon, 2/7/2011 | 6:15 PM | vs Wilson | W 42-39 |
| Sat, 2/12/2011 | 2:30 PM | vs Kutztown | W 60-36 |
| Tue, 2/15/2011 | 6:30 PM | vs Daniel Boone | W 57-54 |
| Fri, 2/18/2011 | 6:30 PM | at Wilson | W 41-51 |
| Tue, 2/22/2011 | 7:00 PM | vs Central Dauphin East | W 56-44 |
| Fri, 2/25/2011 | 8:00 PM | vs Daniel Boone | W 54-47 |
| Mon, 2/28/2011 | 5:00 PM | at Red Lion | L 43-38 |
| Thu, 3/3/2011 | 8:00 PM | at Muhlenberg | W 36-58 |
| Fri, 3/11/2011 | 5:00 PM | vs Cheltenham | L 46-74 |
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