| Date | Time | Opponent | Score |
| Fri, 12/10/2021 | 6:00 PM | vs Pottsville | W 45-23 |
| Sat, 12/11/2021 | 5:30 PM | vs Easton | W 52-40 |
| Tue, 12/14/2021 | 6:00 PM | at Lancaster Catholic | W 35-52 |
| Fri, 12/17/2021 | 6:00 PM | at Gov. Mifflin | L 54-52 |
| Tue, 12/21/2021 | 6:00 PM | vs Reading High | L 36-64 |
| Mon, 12/27/2021 | 7:30 PM | at Hempfield | L 51-50 |
| Tue, 12/28/2021 | 6:00 PM | vs Bishop McDevitt | W 58-51 |
| Mon, 1/3/2022 | 6:00 PM | at Exeter | L 48-47 |
| Thu, 1/6/2022 | 6:00 PM | vs Muhlenberg | W 57-56 |
| Tue, 1/11/2022 | 6:00 PM | vs Berks Catholic | W 51-48 |
| Thu, 1/13/2022 | 6:00 PM | vs Fleetwood | W 73-53 |
| Mon, 1/17/2022 | 6:00 PM | vs Conrad Weiser | W 56-50 |
| Fri, 1/21/2022 | 6:00 PM | at Twin Valley | W 44-62 |
| Sat, 1/22/2022 | 1:00 PM | vs Downingtown West | L 47-60 |
| Tue, 1/25/2022 | 6:00 PM | vs Gov. Mifflin | W 54-43 |
| Mon, 1/31/2022 | 6:00 PM | vs Exeter | W 63-49 |
| Wed, 2/2/2022 | 6:00 PM | at Harrisburg | W 55-67 |
| Thu, 2/3/2022 | 6:00 PM | at Daniel Boone | W 31-62 |
| Sat, 2/5/2022 | 1:00 PM | vs Methacton | W 60-56 |
| Tue, 2/8/2022 | 6:00 PM | at Berks Catholic | L 56-43 |
| Wed, 2/9/2022 | 6:00 PM | at Reading High | L 89-55 |
| Mon, 2/14/2022 | 7:00 PM | vs Exeter | L 51-55 |
| Tue, 2/22/2022 | 7:00 PM | at Waynesboro | W 47-61 |
| Fri, 2/25/2022 | 7:00 PM | at Reading High | L 68-45 |
| Tue, 3/1/2022 | 7:00 PM | at Hempfield | L 56-47 |
| Fri, 3/4/2022 | 7:00 PM | at Cumberland Valley | L 44-41 |
|