| Date | Time | Opponent | Score |
| Fri, 12/10/2021 | 7:00 PM | at Pottsgrove | L 64-37 |
| Sat, 12/11/2021 | 7:00 PM | at Pottstown | L 61-46 |
| Wed, 12/15/2021 | 6:00 PM | at Fleetwood | L 71-18 |
| Fri, 12/17/2021 | 6:00 PM | vs Muhlenberg | L 26-80 |
| Tue, 12/21/2021 | 6:00 PM | at Conrad Weiser | L 67-32 |
| Thu, 12/23/2021 | 7:00 PM | vs Antietam | L 29-54 |
| Tue, 12/28/2021 | 5:00 PM | at Pottsgrove | L 62-28 |
| Wed, 12/29/2021 | 7:00 PM | at Schuylkill Valley | L 58-47 |
| Thu, 12/30/2021 | 6:00 PM | vs Wyomissing | L 45-56 |
| Mon, 1/3/2022 | 6:00 PM | at Gov. Mifflin | L 69-28 |
| Mon, 1/10/2022 | 6:00 PM | at Oley Valley | L 65-38 |
| Tue, 1/11/2022 | 6:00 PM | at Twin Valley | L 68-50 |
| Thu, 1/13/2022 | 6:00 PM | at Exeter | L 76-40 |
| Mon, 1/17/2022 | 6:00 PM | vs Berks Catholic | L 26-80 |
| Wed, 1/19/2022 | 6:00 PM | at Reading High | L 111-43 |
| Sat, 1/22/2022 | 12:00 PM | vs Pottstown | L 41-56 |
| Wed, 1/26/2022 | 6:00 PM | vs Twin Valley | L 52-66 |
| Fri, 1/28/2022 | 6:00 PM | at Muhlenberg | L 82-17 |
| Mon, 1/31/2022 | 6:00 PM | vs Conrad Weiser | L 46-70 |
| Thu, 2/3/2022 | 6:00 PM | vs Wilson | L 31-62 |
| Sat, 2/5/2022 | 12:00 PM | vs Owen J. Roberts | L 32-59 |
| Wed, 2/9/2022 | 6:00 PM | at Manheim Central | L 71-36 |
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