| Date | Time | Opponent | Score |
| Fri, 12/10/2021 | 7:00 PM | vs Steel-High | W 45-38 |
| Sat, 12/11/2021 | 7:00 PM | at Hanover | W 44-58 |
| Wed, 12/15/2021 | 6:00 PM | vs Daniel Boone | W 71-18 |
| Fri, 12/17/2021 | 6:00 PM | at Hamburg | W 38-46 |
| Tue, 12/28/2021 | 7:00 PM | vs Pequea Valley | W 64-19 |
| Wed, 12/29/2021 | 7:00 PM | vs Brandywine Heights | W 49-47 |
| Thu, 1/6/2022 | 6:00 PM | vs Kutztown | W 62-24 |
| Sat, 1/8/2022 | 1:00 PM | at Manheim Central | L 66-55 |
| Tue, 1/11/2022 | 6:00 PM | vs Schuylkill Valley | W 54-49 |
| Thu, 1/13/2022 | 6:00 PM | at Wilson | L 73-53 |
| Fri, 1/14/2022 | 6:00 PM | at Oley Valley | L 52-48 |
| Sat, 1/22/2022 | 6:00 PM | at Wyomissing | W 25-52 |
| Tue, 1/25/2022 | 6:00 PM | vs Hamburg | W 76-45 |
| Wed, 1/26/2022 | 6:00 PM | vs Antietam | W 51-38 |
| Thu, 1/27/2022 | 6:00 PM | vs Twin Valley | W 60-41 |
| Sat, 1/29/2022 | 5:30 PM | at Tulpehocken | L 59-51 |
| Mon, 1/31/2022 | 6:00 PM | vs Wyomissing | W 53-44 |
| Wed, 2/2/2022 | 6:00 PM | vs Catasauqua | W 65-16 |
| Thu, 2/3/2022 | 6:00 PM | at Brandywine Heights | W 36-55 |
| Sat, 2/5/2022 | 1:00 PM | at Palisades | L 67-62 |
| Tue, 2/8/2022 | 6:00 PM | at Schuylkill Valley | W 50-56 |
| Mon, 2/14/2022 | 7:00 PM | at Muhlenberg | L 70-48 |
| Mon, 2/21/2022 | 7:00 PM | at Hershey | L 73-48 |
| Thu, 2/24/2022 | 7:00 PM | at Palmyra | L 67-46 |
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